Yeditepe University Hospital

Koşuyolu Street No:168, 34718 Kadıköy, Istanbul

Contact

4447000

Mon - Fri: 9:00 - 17:30

Carotid Artery Disease — Frequently Asked Questions

25 Questions and Answers

Carotid artery disease is the narrowing or complete blockage of the carotid arteries — the vessels that carry oxygen and nutrients to the brain — due to the build-up of cholesterol, fat, and calcium plaques on their inner walls. Reduced blood flow means the brain receives insufficient oxygen, creating a risk of transient ischaemic attack (TIA) or permanent stroke. The condition usually progresses slowly and, if not diagnosed early, can lead to permanent brain damage.

Carotid artery disease often progresses silently. However, temporary symptoms may occur, including brief loss of vision, speech difficulties, numbness on one side of the face or body, loss of balance, or weakness in an arm or leg. These findings indicate a "mini stroke" and warn of serious stroke risk. Even if symptoms last only a few minutes, medical attention must be sought immediately.

The disease is most common in older individuals and in those with high blood pressure, high cholesterol, or diabetes. Smoking, obesity, a sedentary lifestyle, and a diet high in salt and fat also increase risk. It is slightly more frequent in men, but the rate also rises in women after menopause. Anyone with a family history of stroke or cardiovascular disease should have regular screening.

As the blockage progresses, clots that break off from plaques travel to the brain and block small vessels there. This deprives brain tissue of oxygen, causing a stroke. Stroke can result in the death of brain cells within minutes. Carotid artery disease is therefore one of the most common causes of stroke, and early intervention saves lives.

Yes, because every narrowing has the potential to progress. A stenosis that starts at 30–40% can rise above 70% over time. These plaques can also break off and send clots to the brain. The idea that "a small narrowing doesn't matter" is incorrect; Doppler ultrasound check-ups at intervals set by the doctor must not be neglected.

The first step is a neck Doppler ultrasound. If necessary, CT angiography, MR angiography, or conventional angiography is used to clarify the degree of stenosis. These methods allow assessment of the location, extent, and clot risk of the blockage. Cholesterol, blood sugar, and blood pressure levels are also measured to analyse overall vascular health.

Treatment depends on the degree of narrowing. Mild stenosis is managed with medication (anticoagulants, cholesterol-lowering drugs) and lifestyle changes. Moderate to severe stenosis may require surgical endarterectomy (cleaning the inside of the vessel) or stenting. Appropriate patient selection is critical and is determined by a surgeon or interventional cardiologist.

It depends on the individual. Stenting is more comfortable for young patients with suitable anatomy. However, surgical endarterectomy may provide a more durable solution for heavily calcified or long-segment stenoses. Both methods can be performed with low risk in experienced centres. The goal is to safely restore blood flow to the brain.

For mild stenosis, yes. Medication, blood pressure and cholesterol control, quitting smoking, exercising, and eating healthily can halt progression. However, if plaque volume is high or clot risk is elevated, medication alone is insufficient.

Yes, they make a significant difference. Thirty minutes of walking per day, a diet low in saturated fat, reducing salt and sugar, quitting smoking entirely, and keeping blood pressure below 130/80 mmHg all noticeably improve vascular health. Cholesterol-lowering medications also support regression of plaques.

Smoking directly damages the vessel wall, reduces oxygen-carrying capacity, and increases the tendency to clot. Carotid artery disease is 2–3 times more common in smokers. Quitting smoking is the single most effective step in halting disease progression.

Uncontrolled high blood pressure exerts constant pressure on vessel walls, causing micro-tears. Fat and cholesterol accumulate more easily at these sites. It is therefore essential for hypertensive patients to take their medication regularly and reduce salt intake.

LDL ("bad" cholesterol) sticks to the inner vessel wall and forms plaques. Over time these plaques harden, crack, and generate clots. Lowering cholesterol stops these plaques from growing and reduces stroke risk.

A carotid bruit may be detected on physical examination. The vessel is then imaged with Doppler ultrasound and MR/CT angiography. A lipid profile, glucose, and kidney function tests are also carried out. Brain MRI may be performed if needed to assess silent ischaemic areas.

At least one Doppler scan is recommended for individuals over 65 who have smoked, have high blood pressure, or have diabetes. Regular check-ups after age 55 are beneficial for those with a family history of stroke.

Yes. Risk increases in women after menopause as the protective effect of oestrogen declines. Use of oral contraceptives combined with smoking raises the risk further.

Carotid endarterectomy generally takes 1–2 hours. In experienced hands, the stroke risk is below 2%. It can even be performed under local anaesthesia. Patients are usually discharged within 1–2 days.

Patients typically return to normal activities within a few days. The incision heals quickly. Regular medication, blood pressure control, and adherence to dietary recommendations are required.

Plaque can develop in the other carotid artery over time. Annual Doppler follow-up is therefore recommended. Since both arteries supply the brain, if one is blocked the other bears a greater burden.

Yes — aspirin or similar anticoagulants and cholesterol-lowering drugs should be used long-term. These medications prevent new clot formation and reduce stroke risk.

It can, though rarely. It usually develops when risk factors are not controlled. The likelihood of re-stenosis is higher in people who continue smoking or fail to lower their cholesterol.

Yes. Regular exercise (walking, light aerobics) is recommended with the doctor's guidance. However, activities that raise blood pressure significantly — such as heavy lifting or intense sport — should be avoided.

A Mediterranean-style diet is recommended: olive oil, fish, vegetables and fruit, whole grains, and limited salt and processed food. Animal fat, red meat, and butter should be restricted.

Sudden speech difficulty, one-sided weakness, vision loss, or dizziness should prompt an immediate visit to the emergency department without delay.

It can be largely prevented by controlling all risk factors. Not smoking, regular exercise, a healthy diet, and blood pressure and cholesterol control are the most effective protective measures.